Moxifen, testolactone and the nonsteroidal anti-inflammatory drugs) andcytotoxic agents (methotrexate, vinblastine and doxorubicin). Possible candidates for systemic therapy include patients with Gardner's syndrome and unresectable or recurrent desmoid tumors, involving the mesentery [15]. It must be emphasized that, to date, the evidence regarding the efficacy of these agents are drawn from case reports and single-arm series with small patient numbers [16]. In summary, desmoid tumors are rare and benign neoplasms with a unique biologic behavior. Treatment strategies must be individualized so as to provide adequate local control with subsequent acceptable functional and esthetic outcome. Despite the applied therapeutic method, due PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/6388955 to the high recurrence rate, these patients must be closely followed by clinical examination and radiographic studies.AbbreviationsMRI, Magnetic resonance imaging; RT, Radiation therapy.ConsentWritten informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.Competing interestsThe authors declare that they have no competing interests.Authors' contributionsAll authors contributed equally to this work. KI and KG, performed the surgery, PA and TS performed the pathological examination of the excised specimen, KK, CJ and KN reviewed the current literature. KG, EL and AM contributed in writing and revising the manuscript. All authors read and approved the final manuscript.
Particle and Fibre ToxicologyResearchBioMed CentralOpen AccessUltrafine carbon particles down-regulate CYP1B1 expression in human monocytesChristiane Eder1, Marion Frankenberger1, Franz Stanzel2,5, Albrecht Seidel3, Karl-Werner Schramm4, Loems Ziegler-Heitbrock1 and Thomas PJ Hofer*Address: 1Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Clinical Cooperation Group Inflammatory Lung Diseases, Institute of Lung Biology and Disease and Asklepios Fachkliniken Muenchen-Gauting, Robert-Koch-Allee 29, 82131 Gauting, Germany, 2Asklepios Fachkliniken M chen-Gauting, Robert-Koch-Allee 2, 82131 Gauting, Germany, 3Biochemisches Institut f Umweltcarcinogene, Lurup 4, 22927 Grosshansdorf, Germany, 4Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Institute for Ecological Chemistry, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany and 5Current address: Lungenklinik Hemer, Theo-FuncciusStrasse 1, 58675 Hemer, Germany Email: Christiane Eder - christiane.eder@mll-online.de; Marion Frankenberger - frankenberger@helmholtz-muenchen.de; Franz Stanzel - franz.stanzel@lkhemer.de; Albrecht Seidel - albrecht.seidel@biu-grimmer.de; Karl-Werner Schramm - schramm@helmholtzmuenchen.de; Loems Ziegler-Heitbrock - ziegler-heitbrock@helmholtz-muenchen.de; Thomas PJ Hofer* - hofer@helmholtz-muenchen.de * Corresponding authorPublished: 16 October 2009 Particle and Fibre Toxicology 2009, 6:27 Vorinostat doi:10.1186/1743-8977-6-Received: 4 May 2009 Accepted: 16 OctoberThis article is available from: http://www.particleandfibretoxicology.com/content/6/1/27 ?2009 Eder et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.AbstractBackground: Cyt.